The micropatterns of glutaraldehyde-crosslinked gelatin as ECM for attachment of tumor cells
學年 97
學期 1
發表日期 2009-01-01
作品名稱 The micropatterns of glutaraldehyde-crosslinked gelatin as ECM for attachment of tumor cells
作品名稱（其他語言）
著者 Ou, Yu-Cheng; Hsu, Chih-Wen; Yang, Lung-Jieh; Han, Hsieh-Cheng; Liu, Yi-Wen; Chen, Chien-Yuan
作品所屬單位 淡江大學機械與機電工程學系
出版者 N.Y.: IEEE (Institute of Electrical and Electronic Engineers)
會議名稱 Proc. of 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009, art
會議地點 Shenzhen, China
摘要 Use of this work proposes a novel technique to induce the attachment of tumor cells to the micropatterns of glutaraldehyde (GA)-crosslinked gelatin. It provides another method to crosslink gelatin other than using the photo-sensitizing agents or selective GA-crosslinked technique. The micropatterns of GA-crosslinked gelatin are fabricated by O2 plasma etching process. This novel technique can ensure the degree of crosslink, prevent the over-crosslink from pattern deformation and enhance the adhesion between the gelatin and glass slide. The best spatial resolution of the micro gelatin bases can be reached to 2 mum. The micropatterns of GA-crosslinked gelatin can still be made successfully by the conventional photolithography. The much less toxic and more biocompatible approaches of strengthening the gelatin microstructures can be developed according to the idea herein.
關鍵字
語言 en
收錄於 EI
會議性質 國際
校內研討會地點
研討會時間
通訊作者
國別 CHN
公開徵稿
出版型式
出處 Proc. of 4th IEEE International Conference on Nano/Micro Engineered and Molecular Systems, NEMS 2009, art. no.5068585, pp.314-318
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