期刊論文
| 學年 | 113 |
|---|---|
| 學期 | 2 |
| 出版（發表）日期 | 2025-07-01 |
| 作品名稱 | The updated network meta-analysis of the therapeutic efficacies of lung cancer: A systematic review and meta-analysis |
| 作品名稱（其他語言） | |
| 著者 | Chang Chuan-Hsin; Chien Chih-Cheng; Chang Yue-Cune |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Tzu Chi Medical Journal 37(3), p339-347 |
| 摘要 | Objectives: Lung cancer is one of the most common malignancies worldwide. We aim to investigate the most effective treatments for advanced/nonadvanced stages of lung cancer patients. Materials and Methods: We searched electronic databases to investigate the treatment efficacies of lung cancer. The network meta‑analysis was used to identify the top five most effective therapeutic strategies. A total of 157 studies were collected with a cumulative total of 164,678 participants. Results: The results showed that the best top five treatments: (1) for advanced lung cancer in response rate, were Chemo + Chemotherapy + Targeted Therapy, Cell therapy + Immunotherapy, Targeted Therapy + Radiotherapy, Chemoradiotherapy + Immunotherapy, and Chemotherapy + Chemoradiotherapy with cumulative probabilities 50.5, 49.6, 47.7, 46.0, and 45.6%; (2) for advanced lung cancer in progression‑free survival (PFS) rate, were Targeted + Radiotherapy, Targeted + Others Therapy, Targeted + Targeted Therapy, Immu + Immu + Chemo Therapy, and Chemoradiotherapy with cumulative probabilities 99.5, 82.8, 44.9, 36.5, and 33.6%; (3) for nonadvanced lung cancer in response rate, were Chemoradiotherapy + Immu, Chemoradiotherapy + Targeted therapy, Chemoradiotherapy + Others, Chemotherapy + Surgery, and Radiotherapy + Others with cumulative probabilities 79.1, 74.9, 66.9, 60.4, and 54.2%; (4) for non‑advanced lung cancer in PFS rate, were Chemo + Surgery, Chemoradiotherapy + Targeted, Surgery, Surgery + Radiotherapy, and Chemoradiotherapy + Others with cumulative probabilities 88.3, 86.1, 78.3, 73.1, and 50.8%. Conclusion: We present the latest and most effective therapeutic strategies for patients with advanced or nonadvanced stages of lung cancer. |
| 關鍵字 | Lung cancer; Network meta-analysis; Therapeutic efficacy |
| 語言 | en_US |
| ISSN | 1016-3190 |
| 期刊性質 | 國內 |
| 收錄於 | ESCI |
| 產學合作 | |
| 通訊作者 | Yue-Cune Chang |
| 審稿制度 | 是 |
| 國別 | TWN |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/127674 ) |