期刊論文
| 學年 | 102 |
|---|---|
| 學期 | 2 |
| 出版（發表）日期 | 2014-03-27 |
| 作品名稱 | Synthesis of 3-Substituted Indole by AlCl3 Promoted Reaction of α,β-Unsaturated Ketone with Indole |
| 作品名稱（其他語言） | |
| 著者 | Lee, Shih-yuan |
| 單位 | |
| 出版者 | |
| 著錄名稱、卷期、頁數 | Research on Chemical Intermediates 40, p.2277-2285 |
| 摘要 | A one-pot Lewis acid-promoted reaction condition of β,γ-unsaturated ketone with indole was developed for the synthesis of 3-substituted indoles with moderate to good yields. A Lewis acid such as AlCl3 was shown to be a promising promoter for in situ isomerization of β,γ-unsaturated ketone to its corresponding α,β-unsaturated ketone, then undergoing Friedel–Crafts Michael addition reaction with indole to afford 3-substituted indole. |
| 關鍵字 | Friedel–Crafts reaction Michael reaction;3-Substituted indole;β,γ-Unsaturated ketone;α,β-Unsaturated ketone |
| 語言 | en_US |
| ISSN | 1568-5675 |
| 期刊性質 | 國外 |
| 收錄於 | SCI |
| 產學合作 | |
| 通訊作者 | Adam Shih-Yuan Lee |
| 審稿制度 | 是 |
| 國別 | USA |
| 公開徵稿 | |
| 出版型式 | ,電子版,紙本 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/111782 ) |