期刊論文

學年 88
學期 2
出版(發表)日期 2000-04-01
作品名稱 Efficient syntheses of (−)-shikimate and (−)-quinate 3-phosphate via trans vicinal diol protection with 2,2,3,3-tetramethoxybutane (TMB) of shikimic and quinic acids
作品名稱(其他語言)
著者 Shih, Tzenge-lien; Wu, S. H.
單位 淡江大學化學學系
出版者
著錄名稱、卷期、頁數 Tetrahedron letters41, pp.2957-2959
摘要 (−)-Shikimate 3-phosphate and (−)-quinate 3-phosphate can be synthesized by selective protection of their trans diol functionality using 2,2,3,3-tetramethoxybutane (TMB) using d-(−)-shikimic acid and d-(−)-quinic acid as starting materials. This versatile reagent facilitates the synthesis of these important biological targets in fewer steps than previously reported. By the proper choice of protecting group for C-3 hydroxyl in d-(−)-quinic acid, it can be converted to a key intermediate in the synthesis of (−)-shikimate 3-phosphate.
關鍵字 shikimic acid;quinic acid;shikimate 3-phosphate;quinate 3-phosphate;2,2,3,3-tetramethoxybutane
語言 en
ISSN
期刊性質 國內
收錄於
產學合作
通訊作者
審稿制度
國別 TWN
公開徵稿
出版型式 ,電子版
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