期刊論文
學年 | 88 |
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學期 | 2 |
出版(發表)日期 | 2000-04-01 |
作品名稱 | Efficient syntheses of (−)-shikimate and (−)-quinate 3-phosphate via trans vicinal diol protection with 2,2,3,3-tetramethoxybutane (TMB) of shikimic and quinic acids |
作品名稱(其他語言) | |
著者 | Shih, Tzenge-lien; Wu, S. H. |
單位 | 淡江大學化學學系 |
出版者 | |
著錄名稱、卷期、頁數 | Tetrahedron letters41, pp.2957-2959 |
摘要 | (−)-Shikimate 3-phosphate and (−)-quinate 3-phosphate can be synthesized by selective protection of their trans diol functionality using 2,2,3,3-tetramethoxybutane (TMB) using d-(−)-shikimic acid and d-(−)-quinic acid as starting materials. This versatile reagent facilitates the synthesis of these important biological targets in fewer steps than previously reported. By the proper choice of protecting group for C-3 hydroxyl in d-(−)-quinic acid, it can be converted to a key intermediate in the synthesis of (−)-shikimate 3-phosphate. |
關鍵字 | shikimic acid;quinic acid;shikimate 3-phosphate;quinate 3-phosphate;2,2,3,3-tetramethoxybutane |
語言 | en |
ISSN | |
期刊性質 | 國內 |
收錄於 | |
產學合作 | |
通訊作者 | |
審稿制度 | 否 |
國別 | TWN |
公開徵稿 | |
出版型式 | ,電子版 |
相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/61579 ) |