期刊論文
| 學年 | 91 |
|---|---|
| 學期 | 2 |
| 出版（發表）日期 | 2003-04-01 |
| 作品名稱 | B- to S-form transition in double-stranded DNA with basepair interactions |
| 作品名稱（其他語言） | |
| 著者 | Lai, Pik-yin; 周子聰; Zhou, Zi-cong |
| 單位 | 淡江大學物理學系 |
| 出版者 | Elsevier |
| 著錄名稱、卷期、頁數 | Physica A: Statistical Mechanics and its Applications 321(1-2), pp.170-180 |
| 摘要 | When a DNA in its nature double-helical state is stretched by an external force, its length undergoes a sharp extension from the B-form to the 1.7 times elongated S-form. This phenomenon is investigated in the framework of a model of a double-stranded with basepair interactions and bending. Shape equations governing the structure of the DNA under external forces and torques are derived using a classical mechanical approach. The first-order nature of the B- to S-form transition is revealed clearly in terms of an effective potential with a barrier separating these two states. All the structural properties of the DNA in both forms can be calculated in detail. The configurations of the double strands, relative extension, amount of self-untwisting and the threshold stretching force of the DNA under stretched are obtained and compare well with experimental observations. |
| 關鍵字 | Biopolymer;DNA |
| 語言 | en |
| ISSN | 0378-4371 |
| 期刊性質 | 國內 |
| 收錄於 | |
| 產學合作 | |
| 通訊作者 | |
| 審稿制度 | 否 |
| 國別 | TWN |
| 公開徵稿 | |
| 出版型式 | ,電子版 |
| 相關連結 |
機構典藏連結 ( http://tkuir.lib.tku.edu.tw:8080/dspace/handle/987654321/27710 ) |